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Anti-Aging Ingredient | Definition | What They Do

20-glycolic-acid-lotion.jpgAuthor: Mary Gillespie

Do you G-PAC? Glycolic, Peptides, topical vitamins A and C ... even dermatologists say “get going!”

Skin911 glycolic liquids, gels and creams will fast track you there…we stand behind our products 100%.

Studies show combining glycolic, an alpha hydroxy acid, and prescription Vitamin A retinoic acid (tretinoin) such as, .05% Tazorac Gel® or .04% Retin-A Micro Gel® give you a better result than if used separately for aging.


Cosmetic Dermatology, Volume 6, No 10, Oct 1993, "Results of a Pilot Study Evaluating the Compatibility of Topical Tretinoin in Combination with Glycolic Acid" by Albert Kligman, M.D., Ph.D.

The Journal of Geriatric Dermatology, Volume 1, Number 4, Winter 1993 "Compatibility of a Glycolic Acid Cream with Topical Tretinoin for the Treatment of the Photo Damaged Face of Older Women" by Albert Kligman, M.D., Ph.D.

Higher strengths of prescription retinoic acid such as, Renova®, Retin-A®, Tazorac® and Avage® can quickly produce high side effects of redness, irritation, dryness, flaking and sun sensitivity if used too often in the beginning. Glycolic has two possible side effects, dryness and sensitivity which take longer to show up, usually in the first weeks giving you a chance to cut back your applications until your skin adjusts. Starting Skin911's glycolic program first, then gradually adding retinoic acid until applying once daily with your twice daily glycolic products is the easiest program. The results are superb and well worth the effort, remember to increase the strength of your retinoic acid every seven years to combat your skin’s tolerance.

How do I apply Skin911 glycolic and retinoic acid?

  • Rule of thumb, retinoic acid is applied first to your skin with Skin911 glycolic liquid, gel or cream over the top making use of its delivery agent.
  • The exception, involves the retinoic acid "vehicle" or base used to apply retinoic acid to your skin. If a gel, then apply Skin911 products over the top, if using two creams apply retinoic first with Skin911 over the top, if using retinoic cream and Skin911 liquid or gel apply the Skin911 first with the cream over the top. Liquids or gels are not easily applied over creams, and should be applied first but creams are applied over creams.

How often do I apply retinoic acid at first?

  • Start by using Skin911 glycolic liquid, gel or cream comfortably twice daily, then add retinoic acid once every seventh day for two weeks. If not experiencing side effects apply every sixth day for two weeks, then every fifth day for two weeks. Every two weeks reduce the days between your last application of retinoic acid until using once a day with Skin911 glycolic products twice daily. Return to the last step if experiencing dryness or sensitivity. Increase the strength of your Skin911 products one container at a time.

What’s the difference between retinoic acid (tretinoin) and retinyl palmitate (retinol) for aging?

  • Both are derivatives of Vitamin A but divided into two categories by the FDA (Food and Drug Administration).
  • Retinyl palmitate is a non-prescription OTC (over the counter) for all skin types converting to retinoic acid at the cell site using an enzyme in your skin. Since skin lacks high levels of this enzyme the conversion rate is low making it ideal for sensitive skin types without irritation.
  • Retinoic acid (tretinoin) is only available with a doctor’s prescription and comes straight from the tube to your skin at the prescribed strength. Due to its strength the results for severe or premature aging are better but can have dryness and irritation side effects if applied too often in the beginning. Retin-A Micro 0.1% ®, a tretinoin gel with time-release micro sponges retains its efficacy and is compared to .025% tolerance (low side effects).
  • These ingredients marketed and patented for acne and aging combined with glycolic acid have shown dramatic results in studies. It's never too late to begin the combination starting with retinyl palmitate.

What is a peptide?

  • Any group of organic compounds comprising two or more amino acids which react by forming a link or peptide bond. Amino acids are the building blocks of protein reduced to protein fragments or peptides, they communicate, or interact with target molecules in your body to prompt, or start an activity the body has slowed, or stop performing.
  • Peptide technology is remarkable proving its ability to penetrate your skin without redness or irritation. Excellent for all skin types, especially sensitive and ultra sensitive wanting anti-aging results, and can be combined with any pharmaceutical, or cosmetic due to its gentle nature.
  • Found its niche in the skin care industry as the “communicator” turning-off the command to age, and turning-on the command to repair, an ambassador to your skin’s network circuit board.

Why topical vitamin C as L-ascorbic acid?

  • "L-ascorbic acid is the only form of vitamin C the body can recognize and use." Sheldon R. Pinnell, M.D., Chief, Dermatology and J. Lamar Callaway Professor of Dermatology, Duke University Medical Center, Durham, N.C.
  • The one vitamin doctors agree can speed wound healing, protect fatty tissues from oxidation damage, play an integral role in collagen synthesis, and essential for the growth and maintenance of connective tissue.
  • Now, being recognized for its active role in the prevention of aging skin.
  • Even though, your diet may contain adequate amounts of vitamin C doesn’t necessarily mean it will reach your skin, particularly for overly sun-exposed. Sunlight, smoking, and environmental conditions cause damage to the fragile capillary pathways feeding your skin. Nutrients circulating in the bloodstream can no longer reach the skin in adequate amounts, without these essential components skin cells can’t make healthy collagen needed for maintaining firm, and youthful looking skin, topical L-ascorbic acid solves this problem.